About the job

Our Team:

Are you ready to shape the future of medicine? The race is on to leverage cutting-edge robotics and AI to drive breakthroughs in compound discovery and optimization. Your skills will be critical in helping our teams to discovery better drugs efficiently.

Join our dynamic team at Sanofi Germany (Frankfurt) in the Integrated Drug Discovery department.  We are working at the cutting edge of innovation leveraging robotics and artificial intelligence and are currently building an integrated laboratory enabling seamless execution of the full Design-Make-Test-Analyze (DMTA) cycle to accelerate compound discovery and optimization.

We are seeking an experienced Scientist to join our team in the computer-assisted-drug-design department of Integrated Drug Discovery at Sanofi Germany (Frankfurt). The successful candidate will be responsible for developing and optimizing new automated design approaches for Design-Make-Test-Analyze (DMTA) cycles, explore new scientific ways to improve the efficiency and quality of drug discovery processes and actively participate in shaping our future integrated laboratory.

The role further includes the development of novel AI-based design and analysis approaches to integrate them seamlessly into automated workflows and our robotic lab environment. With this, you will advance the science of AI in drug design within our group and evaluate key opportunities for applying them in drug discovery projects. Furthermore, you will strongly contribute to the discovery of novel molecules with state-of the art technologies for AI and computer-aided drug design.

Main responsibilities:

• Advancing artificial intelligence technologies in the field of drug discovery and drive the development of de novo design technologies in combination with multiparameter optimization and computational chemistry technologies
• Design, optimization and application of automated AI-based approaches for the successful design of novel drug molecules
• Development of strategies for automated molecule generation, data analysis, and model optimization and seamless integration of workflows into existing ecosystems to feed into automated lab environments
• Systematically analyze large data sets for the design of novel molecules  
• Playing an active role in multidisciplinary drug discovery teams consisting of medicinal chemists, automation scientists, and biologists and being an active member of the computational and medicinal chemistry community
• Working within an agile team of digital scientists to develop artificial intelligence technologies across domains
• Communicate results to experts from different scientific areas and explain methodologies and analytical findings to peers and customer stakeholders

About you

Experience:

• ≥5 years of professional experience in in-silico drug discovery or in automated workflow development
• Track record of productivity in the areas of computational chemistry, artificial intelligence, machine learning, medicinal chemistry
• Expertise in automated workflows and experience in efficient implementation of automated data analysis and design workflows
• Proven problem solving abilities

Soft and technical skills:

• Expert knowledge in machine learning and artificial intelligence combined with a strong knowledge of computational drug design methods
• Strong programming skills including proficiency in Python
• Strong background in medicinal chemistry
• Understanding of database systems and data retrieval technologies
• Strong interpersonal, organizational and communication skills and team player/collaborative spirit with a strong passion for science

Education:

• PhD in Life Sciences, esp. in computational chemistry, medicinal chemistry or pharmaceutical sciences.

Languages:

• Fluency in English, German is a plus

Why choose us?

• Bring the miracles of science to life alongside a supportive, future-focused team.
• Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.
• Benefit from a well-thought-out benefits package that rewards your contribution and commitment.
• We take care of you and your family with a wide range of health and social such as high-quality healthcare, numerous prevention programs and coverage for long-term illness. Our 14-week paid family leave for both parents is outstanding as well as a wide range of childcare benefits.

“As a key figure in our cutting-edge lab, this role is essential for operating the lab, developing protocols, and ensuring the excellence of our automated systems.”
Dr. Gerhard Hessler, Head of Synthetic Molecular Design

Pursue Progress. Discover Extraordinary.

Progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. You can be one of those people. Chasing change, embracing new ideas and exploring all the opportunities we have to offer. Let’s pursue progress. And let’s discover extraordinary together.

At Sanofi, we provide equal opportunities to all regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, or gender identity.
 

Watch our ALL IN video and check out our Diversity Equity and Inclusion actions at sanofi.com!

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Pursue progress, discover extraordinary

Better is out there. Better medications, better outcomes, better science. But progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let’s be those people.

At Sanofi, we provide equal opportunities to all regardless of race, colour, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, ability or gender identity.

Watch our ALL IN video and check out our Diversity Equity and Inclusion actions at sanofi.com!